R & D

Wise’s R&D efforts leverage a proprietary engine developed through co-Founder Dr. Tracy Dennis-Tiwary’s pioneering academic work in Attention Bias Modification Treatment (ABMT).​

Wise’s R&D pipeline includes both “over the counter” and prescription digital therapeutics​

Dr. Dennis-Tiwary’s extensive clinical research can be found here.

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Personal Zen
Digital therapeutic targeting stress and anxiety

Wise’s flagship product, Personal Zen, is a gamified micro-intervention for stress and anxiety reduction developed and validated through numerous randomized placebo-controlled clinical trials. Our proprietary engine uses the cognitive therapy technique ABMT to promote greater cognitive flexibility and alleviate disruptive habits of attention that cause and sustain anxiety.

We have integrated our engine into a an engaging, gamified experience for the user. Moreover, Personal Zen is a micro-intervention so it is time-effective: Using it just a few minutes a day, a few days a week effectively reduces feelings of stress and anxiety, strengthens well-being, and builds stress resilience.

Visit personalzen.com for more about the science behind Personal Zen. 

Praise for Personal Zen

“Personal Zen brings cutting-edge research and well-established strategies for reducing anxiety and stress into the palm of your hand.”
Dr. Shannon M. Bennett
Assistant Professor of Psychology in Psychiatry, Weill Cornell Medical College
“Instantly engaging for adults and kids, Personal Zen is a rare example of science turned into fun in order to reduce stress and anxiety.”
Dr. Tony Simon
Professor of Psychiatry & Behavioral Sciences, University of California Davis
“It has helped me tremendously... I love how the app is in a fun, non-threatening game with the sprites.”
Maria M.
Kokomo, Indiana